We are interested in mechanical interactions of biological cells and the extra-cellular matrix and how they affect cell behavior.
In the recent decade it became evident that mechanical interactions can be as important for cells as biochemical ones. Our research aims at elucidating the complex interplay of mechanical and biochemical interactions affecting cell fate, e.g. differentiation of adult mesenchymal stem cells.
We are employing state-of-the art microscopy techniques as well as optical trapping, atomic force microscopy and bulk rheology to study mechanical properties of living systems and their response to mechanical cues.